| 1. | Columbia U., Herbert and Florence Irving Medical Center, and NewYork-Presbyterian/Columbia U. Irving Medical Center | Florence Irving and her late husband, Herbert Irving | food distribution | $600 million (bequest) | recruitment of scientists and clinicians, improvements in patient care, and expansion of cancer center |
| 2. | U. of California at San Francisco | Helen Diller Foundation | husband’s real-estate business | $500 million (bequest) | faculty recruitment, scholarships, biomedical research |
| 3. | Columbia U. College of Physicians and Surgeons | P. Roy and Diana T. Vagelos | pharmaceutical companies | $250 million | scholarships, support for precision-medicine programs, and research |
| 4. | U. of Maryland at College Park | A. James and Alice B. Clark Charitable Foundation (Alice B. Clark) | construction | $219.5 million | scholarships, fellowships, professorships, and a new engineering building and programs in the A. James Clark School of Engineering |
| 5. | U. of California at Irvine | Henry and Susan Samueli | manufacture of semiconductors | $200 million | creation of and support for the Susan and Henry Samueli College of Health Sciences, which will focus on interdisciplinary integrative health |
| 6. | U. of Illinois at Urbana-Champaign | Larry and Beth Gies | holding company | $150 million | programming and scholarships in the business school |
| 7. | Massachusetts Institute of Technology | Anonymous | n/a | $140 million (pledge) | unrestricted use |
| 8. | U. of Chicago | Kenneth C. Griffin Charitable Fund (Kenneth Griffin) | hedge fund | $125 million | financial aid, research, and the recruitment of more professors in the economics department |
| 9. | U. of Hawaii-Manoa | Jay H. Shidler | commercial real-estate company | $117 million (cash and land) | improvement and expansion of the Shidler College of Business |
| 10. | Boston U. | Rajen Kilachand | multinational development company | $115 million | construction funds and endowment for the new Rajen Kilachand Center for Integrated Life Sciences & Engineering |
| 11. | U. of Cambridge | Ray and Dagmar Dolby Family Fund (Ray and Dagmar Dolby) | audio-equipment company | $114.1 million | support for Cavendish Laboratory, a center for physics research |
| 12. | California Polytechnic State U. at San Luis Obispo | William and Linda Frost | chemical-manufacturing company | $110 million | a new interdisciplinary research center, updated equipment, and the hiring of more instructors in the College of Science and Mathematics |
| 13. | Colby College Museum of Art | Peter and Paula Lunder | shoe company | $100 million (value of art) | addition of more than 1,100 artworks to the museum’s collection and creation of the Lunder Institute for American Art |
| 13. | Santa Clara U. | John and Susan Sobrato | property-development company | $100 million | construction of a Sobrato Campus for Discovery and Innovation to promote cross-disciplinary undergraduate teaching and research |
| 13. | U. of Chicago Medicine | Craig and Janet Duchossois, and the Duchossois Family Foundation | holding company | $100 million (pledge) | creation of the Duchossois Family Institute to develop “a new science of wellness” through research and other interventions |
| 13. | U. of Notre Dame | Kenneth and Pamela Ricci | holding company for private aviation corporations | $100 million (pledge) | unrestricted use |
| 17. | West Texas A&M U. | Paul Engler and the Paul F. and Virginia J. Engler Foundation | cattle-ranching and feed business | $80 million (pledge) | support for the renamed Paul Engler College of Agriculture and Natural Sciences and the Paul and Virginia Engler College of Business |
| 18. | Kenyon College | Anonymous | n/a | $75 million | construction of a new library and academic quadrangle |
| 18. | U. of California at San Diego | Taner Halicioglu | former software and operations engineer at Facebook | $75 million | fellowships and scholarships for the new Halicioglu Institute for Data Science |
| 18. | U. of Chicago | Richard and Amy Wallman | technology industry and accounting | $75 million | scholarships for M.B.A. students and other support for the university’s Booth School of Business |
| 21. | Wake Forest U. | Porter B. Byrum | law and business | $70 million (bequest) | endowment for scholarships |
| 22. | Hofstra U./Northwell Health | Donald and Barbara Hrbek Zucker | real-estate-mortgage, development, and other companies | $61-million | scholarships for medical, nursing, and physician-assistant students; program for postdoctoral fellows |
| 23. | California Institute of Technology | Allen V.C. Davis | manufacture of sensors and switches used by airlines and the military | $60 million (bequest) | support for professorships and leadership chairs |
| 23. | U. of Dubuque | Edward Babka and his widow, Shirley Babka | magazine publishing | $60 million (estate pledge) | scholarship fund |
| 25. | Bates College | Michael and Alison Grott Bonney | pharmaceutical company | $50 million | new and modernized facilities for science, technology, engineering, and mathematics programs |
| 25. | Brandeis U. | Rosaline Cohn and Marcia Cohn | family coffee-company wealth | $50 million (bequest) | scholarships and fellowships |
| 25. | Iowa State U. | Jerry and Debbie Ivy | cleaning-machine company | $50 million (pledge) | scholarships, faculty support, and programs in the College of Business |
| 25. | Nova Southeastern U. | Patel Family Foundation (Kiran and Pallavi Patel) | holding company for health-insurance companies and real-estate investments | $50 million | development of a new Tampa Bay Regional Campus in Clearwater, Fla. |
| 25. | Oglethorpe U. | Q. William Hammack Jr. | contracting company | $50 million | creation of the Q. William Hammack, Jr. School of Business |
| 25. | Rochester Institute of Technology | Austin McChord | cybersecurity start-up company | $50 million | support for creativity and entrepreneurship programs, and for artificial-intelligence faculty and graduate students |
| 25. | Saint Joseph’s U. | James Maguire Sr. and Frances Maguire | insurance companies | $50 million | scholarships and a program in risk management and insurance |
| 25. | U. of Kansas | David Booth | international finance firm | $50 million (pledge) | improvements to the university’s Memorial Stadium, construction of an indoor football-practice facility, and other support for athletics |
| 25. | U. of Michigan at Ann Arbor | Stephen Ross | real-estate development firm | $50 million | career-development programs, learning experiences, and faculty support in the Ross School of Business |
| 25. | U. of North Carolina at Chapel Hill | John L. Townsend III and his wife, Marree Townsend | investment company | $50 million (pledge) | $25 million in artworks to the university’s Ackland Art Museum; $25 million for other divisions and programs |
| 25. | U. of Oregon | Anonymous | n/a | $50 million | strategic investments in the university, as chosen by the president |